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The impact of those channels on neuron firing charge in nigral dopamine neurons is this kind of that administration in the KATP-channel antagonist glibenclamide in a 100 nM focus was able to raise neuron firing price by 34% (Garcia de Arriba et al 1999; Avshalumov et al 2005). KATP-channel activity also seems to become improved by extracellular ade